The lab’s research spans several areas of bioinformatics, systems biology and medicine. In bioinformatics, the lab is involved in developing novel strategies for identifying protein interaction networks, intracellular localization of proteins and identification of functional networks in cells. In systems biology, the lab is involved in deciphering mammalian cellular networks from high throughput and phenotypic data and in developing strategies for modeling cellular signaling networks. In systems medicine, we collaborate with biomedical scientists towards understanding diseases associated with insulin resistance and inflammation. Subramaniam’s recent work on systems medicine involves diseases of the skeletal muscle, liver and the immune system. His laboratory is interested in mapping the circuitry of cells to mechanisms and phenotypes in physiology and pathology and to develop quantitative models of cellular pathways.
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