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Positions Available

Posted: August 17, 2007

Available starting immediately

2-3 Postdoctoral Positions

2 Research programmer Positions

The positions are available in the following projects.

1. LIPID MAPS: The major objective of this multiinvestigator multiinstitution project is the identification and characterization of mammalian lipids in normal and diseased states. The cells of choice are macrophages. Work in this project will entail both proteomic annotations and lipid pathway reconstructions. For more information about LIPID MAPS, visit the website; http://www.lipidmaps.org


2. NanoTUMOR project: The major objective of this Center project is the development of nanodevices for detection, monitoring and treatment of cancer. The posted job of Research Programmer is to coordinate data deposition using CaNanoLab architecture and to analyze cellular and phenotypic data from cancer measurements. Required qualifications include web and database experience and familiarity with biology.


3. Gene networks controlling macrophage-adipocyte interactions:  This project  deals with identification and characterization of gene networks in adipocytes and macrophages associated with insulin action. This is a Program Project Grant  involving Professors Chris Glass, Geoff Rosenfeld, Jerry Olefsky and me. We are making systematic genome wide measurements using Chip, ChIP-chip and digital sequencing methods to explore transcriptional changes in adipocytes and macrophages from normal and diseased animals. The work proposed involves using systems biology approaches towards identification and reconstruction of networks, including development of novel strategies.


4. Reconstruction of networks involved in differentiation of stem cells into cardiomyocytes: This  is a systems biology project associated with reconstruction of networks involved in differentiation of murine embryonic stem cells into cardiomyocytes. My co-PIs on this R33 project are Mark Mercola (an embryologist and stem cell biologist) and Juan Carlos Belmonte (a stem cell biologist). We are systematically carrying out both proteomic and gene expression measurements longitudinally with differentiation at various stages. The proposed work will involve analysis of the large data and reconstruction and modeling of networks.

Job applications can be sent by email to Professor Subramaniam at  shankar@ucsd.edu